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. 2014 Feb 28;13:73. doi: 10.1186/1475-2875-13-73

Table 3.

Overall ex - vivo sensitivity of Brazilian isolates for each drug, according to the species tested, and for laboratory P . falciparum (W2 clone) line, chloroquine resistant

Drug
P . falciparum
P . vivax Clinical field isolates
W2
Fc27*
African
Clinical field isolates
  IC 50 (nM) n Median IC 50 (nM)** n Median IC 50 (nM)
Chloroquine
178
39
19
9
70 (0.19-223; 80)
 
32 (3–69; 64)
Artesunate
18
16
1.5
9
1.3 (0.26-5.8; 2.82)
32
21 (0.08-137; 17.4)
Mefloquine 19 11 46 9 21 (1.19-63; 80)   57 (5.0-113; 82)

*Date from Marfurt et al. [28,29]. **The numbers inside of the parenthesis means: lowest IC50, higher IC50 and interquartile range.