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Prevalence of molecular markers associated with P . falciparum resistance to chloroquine
| Gene – codon | % of mutations | Mutations | Protein change |
|---|---|---|---|
|
PfMDR1 |
|
|
|
| 86 |
0% |
- |
- |
| 184 |
100% |
TAT > TTT |
Tyrosine > Phenylalanine |
| 1034 |
84% |
AGT > TGT |
Serine > cysteine |
| 1042 |
100% |
AAT > GAT |
Asparagine > Aspartic acid |
| 1246 |
100% |
GAT > TAT |
Aspartic acid > Tyrosine |
|
PfCRT |
|
|
|
| 72 |
100% |
AAA > ACA |
Lysine > Treonine |
| 76 | 100% | TGT > TCT | Cysteine > Serine |
