Table 3.
Oncologic details in patients who underwent pancreaticoduodenectomy (PD) for pancreatic adenocarcinoma with an aberrant right hepatic artery (PD + aRHA) and standard hepatic arterial anatomy (standard PD)
| Variables | PD + aRHA (n = 37) | Standard PD (n = 212) | P-value |
|---|---|---|---|
| Neoadjuvant therapy, n (%) | 1 (2.7%) | 13 (6.1%) | 0.7 |
| Size, cm, mean ± SD | 3.4 ± 1.4 | 3.1 ± 1.1 | 0.2 |
| Grade (differentiation), n (%) | (n = 35) | (n = 208) | 0.3 |
| Good | 10 (28.6%) | 39 (18.8%) | |
| Moderate | 19 (54.3%) | 139 (66.8%) | |
| Poor | 6 (17.1%) | 30 (14.4%) | |
| Perineural invasion, n (%) | 27 (73.0%) | 162 (76.4%) | 0.09 |
| Lymphovascular invasion, n (%) | 18 (48.6%) | 139 (65.6%) | 0.009 |
| T-stage 1, n (%) | 1 (2.7%) | 9 (4.2%) | 0.9 |
| T-stage 2, n (%) | 3 (8.1%) | 14 (6.6%) | |
| T-stage 3, n (%) | 33 (89.2%) | 183 (86.3%) | |
| T-stage 4, n (%) | 0 | 4 (1.9%) | |
| N1, n (%) | 27 (73.0%) | 159 (75.0%) | 0.8 |
| Number of positive LN | 3 ± 3 | 3 ± 3 | 0.6 |
| Total number of LN | 17 ± 7 | 17 ± 8 | 0.8 |
| LN ratioa | 0.21 ± 0.18 | 0.24 ± 0.17 | 0.4 |
| R1 resection, n (%) | 4 (10.8%) | 34 (16.0%) | 0.4 |
| Type of R1 resection, n (%) | 1.0 | ||
| Retroperitoneal | 3 (75.0%) | 19 (55.9%) | |
| Pancreas | 1 (25.0%) | 13 (38.2%) | |
| Common bile duct | 0 | 1 (2.9%) | |
| Portal vein | 0 | 1 (2.9%) |
a
Defined as the ratio between the number of lymph nodes examined and the number of positive lymph nodes.
SD, standard deviation; LN, lymph nodes.