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. 2014 Mar 6;55(3):1339–1347. doi: 10.1167/iovs.13-13564

Table 2.

Rod Photoresponse Parameters From Single-Cell Recordings


Idark, pA
I1/2, phot μm−2
Tpeak, ms
Tintegr, ms
τrec, ms
τD, ms
iCre75 rods, n = 28 12.8 ± 0.7 21.3 ± 1.7 222 ± 16 528 ± 36 354 ± 24 273 ± 17
iCre75+ rods, n = 21 12.4 ± 0.4 26.1 ± 2.0 171 ± 6* 288 ± 18* 210 ± 13* 166 ± 10*
I

dark, dark current measured from saturated responses; I1/2, half-saturating light intensity; time-to-peak (Tpeak) and integration time (Tintegr) refer to responses with amplitudes < 0.2 Idark that fell within the linear range; τrec, time constant for single-exponential decay of a dim flash response recovery phase; τD, dominant time constant of recovery after supersaturating flashes determined from the linear fit to time in saturation versus intensity semilog plots. Values are mean ± SEM.

*

Indicates significant difference (P < 0.05) compared with control iCre75 rods.