Fig. 5.

Preferential H2A.Z and H4 hyper-acetylation of rDNA in ΔTXR1 cells. Hyper-acetylation of H2A.Z and H4 was associated with the rDNA in ΔTXR1 cells, demonstrated by cross-linking chromatin immuno-precipitation (X-ChIP) using antisera recognizing acetylated H4 and H2A.Z. ChIP samples were quantified by Q-PCR and normalized with input. The numbers on the x-axis denote the median positions of the PCR products. rDNA mini-chromosome sequence (corresponding to half of the palindrome, numbered from the center to one end) was retrieved from GenBank (accession No. X54512).