Fig. 10.

DeCyder topography, gel image analysis, and average log standard abundance of valosin containing protein/p97 (VCP) in response to E2 in young and aged animals. For each panel from top right to left, 3 month: YV representative topography, YE representative topography, YV representative gel image, and YE representative gel image. 18 month: AV representative topography, AE representative topography, AV representative gel image, and AE representative gel image. Graph depicts log transformed average abundance normalized to internal standard and matched to master gel. Average calculated from three independent experiments with a biological variance of four pooled animals per experiment (n = 3, BV = 12). *Significance from vehicle, p < 0.05.