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. 2014 Mar 6;9(3):e87082. doi: 10.1371/journal.pone.0087082

Figure 2. Ratios of plasma cytokines from patients with distinct forms of Chagas disease.

Figure 2

The analysis of plasma levels was performed as described in the material and methods section. The groups evaluated were: NI (n = 24, white box), IND (n = 82, light gray box), and CARD (n = 94, dark gray box). The results are expressed by mean intensity of fluorescence (MIF). A) Ratios between IFN-γ and IL-10 levels in NI, IND, and CARD groups. B) Ratios between TNF-α and IL10 levels in NI, IND, and CARD groups. C) Ratios between IL-6 and IL-10 levels in NI, IND, and CARD groups. D) Ratios between IL-1β and IL-10 levels in NI, IND, and CARD groups. This analysis was employed to determine the balance between high-inflammatory or high-regulatory cytokines and to represent the predominant cytokine profile. Significant differences (P-value<0.05) in the charts are identified by connecting lines and the symbol (*) for comparisons between the groups.