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. 2014 Mar 6;9(3):e90235. doi: 10.1371/journal.pone.0090235

Figure 2. Drug resistance of E. faecalis was evaluated by gradually increasing the concentrations of MTAD, MTADN, and MTAN from 0.5 MIC to 3 MIC.

Figure 2

(A) Asterisks represent a statistically significant difference between E. faecalis survival rates (log10-transformed CFUs counted per milliliter) under treatment with (1) 0.5MIC of MTAN, MTAD and MTADN; (2) MIC of MTAN, MTAD and MTADN; (3) 1.5MIC of MTAN, MTAD and MTADN; (4) 2 MIC of MTAN, MTAD and MTADN; (5) 2.5 MIC of MTAN, MTAD and MTADN; (6) 3 MIC of MTAN, MTAD and MTADN. (B) The bacterial pellet in the eppendorf tube was imaged using a digital camera after treatment with 0.5 to 3.0 MIC of MTAN, MTAD, and MTADN. Square indicated that E. faecalis pellets in the bottom of the centrifugal tubes were found after treatment with 0.5 to 3.0 MIC of MTAD and MTADN, while the circles indicated that bacterial pellets were invisible with 2.0, 2.5, and 3.0 MIC of MTAN.