Table 1. Characteristics of the included studies.
Study | Cases | Controls | |||||||||
Diagnostic | Country | Male | Age | Male | Age | Ref | |||||
criteria | /Area | Ethnicity | Investigated SNPs | N | (%) | (year) | N | (%) | (year) | ||
Bocchio(2002) | DSM-IV | Italy | Caucasian | rs1800896, rs1800871, rs1800872 | 106 | NA | NA | 143 | NA | NA | [20] |
Yu(2004) | DSM-IIIR | China | Asian | rs1800896, rs1800871, rs1800872 | 341 | 54 | 42±16 | 334 | 52 | 42±16 | [21] |
Shirts(2006) | DSM-IV | USA | Caucasian | rs1800872 | 471 | 65 | 38±10 | 453 | 52 | NA | [22] |
Peng(2008) | DSM-IV | Taiwan | Asian | rs1800896, rs1800871, rs1800872 | 659 | 70 | 36±11 | 411 | 43 | 45±14 | [23] |
Ozbey(2009) | DSM-IV | Turkey | Asian | rs1800896, rs1800871, rs1800872 | 171 | 45 | 38±11 | 168 | 45 | 36±15 | [24] |
Almoguera(2011) | DSM-IV | Spain | Caucasian | rs1800896, rs1800871, rs1800872 | 241 | 63 | NA | 435 | 46 | NA | [25] |
PGC(CATIE)(2011) | DSM-IV | USA | Caucasian | rs1800872 | 395 | NA | NA | 391 | NA | NA | [30] |
Jun(2003) | DSM-IV | Korea | Asian | rs1800896 | 233 | 41 | 32 | 181 | 46 | 32 | [26] |
Jun(2002) | DSM-IV | Korea | Asian | rs1800871 | 141 | NA | NA | 146 | NA | NA | [27] |
Paul-Samojedny(2010) | DSM-IV | Poland | Caucasian | rs1800896 | 96 | 38 | 45±12 | 120 | 33 | 39±10 | [28] |
Lung(2011) | DSM-IV | Taiwan | Asian | rs1800896, rs1800871, rs1800872 | 233a | 78 | NA | 433 | 44 | 45±14 | [29] |
PGC(CATIE): data from samples in Clinical Antipsychotic Trials of Intervention Effectiveness of Psychiatric Genomics Consortium; SNPs: single nucleotide polymorphisms; DSM: diagnosis and statistical manual of mental health disorders; NA:not available; aCases after excluding overlapping samples with study [23].