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. 2014 Mar 6;9(3):e90407. doi: 10.1371/journal.pone.0090407

Table 1. Characteristics of the included studies.

Study Cases Controls
Diagnostic Country Male Age Male Age Ref
criteria /Area Ethnicity Investigated SNPs N (%) (year) N (%) (year)
Bocchio(2002) DSM-IV Italy Caucasian rs1800896, rs1800871, rs1800872 106 NA NA 143 NA NA [20]
Yu(2004) DSM-IIIR China Asian rs1800896, rs1800871, rs1800872 341 54 42±16 334 52 42±16 [21]
Shirts(2006) DSM-IV USA Caucasian rs1800872 471 65 38±10 453 52 NA [22]
Peng(2008) DSM-IV Taiwan Asian rs1800896, rs1800871, rs1800872 659 70 36±11 411 43 45±14 [23]
Ozbey(2009) DSM-IV Turkey Asian rs1800896, rs1800871, rs1800872 171 45 38±11 168 45 36±15 [24]
Almoguera(2011) DSM-IV Spain Caucasian rs1800896, rs1800871, rs1800872 241 63 NA 435 46 NA [25]
PGC(CATIE)(2011) DSM-IV USA Caucasian rs1800872 395 NA NA 391 NA NA [30]
Jun(2003) DSM-IV Korea Asian rs1800896 233 41 32 181 46 32 [26]
Jun(2002) DSM-IV Korea Asian rs1800871 141 NA NA 146 NA NA [27]
Paul-Samojedny(2010) DSM-IV Poland Caucasian rs1800896 96 38 45±12 120 33 39±10 [28]
Lung(2011) DSM-IV Taiwan Asian rs1800896, rs1800871, rs1800872 233a 78 NA 433 44 45±14 [29]

PGC(CATIE): data from samples in Clinical Antipsychotic Trials of Intervention Effectiveness of Psychiatric Genomics Consortium; SNPs: single nucleotide polymorphisms; DSM: diagnosis and statistical manual of mental health disorders; NA:not available; aCases after excluding overlapping samples with study [23].