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. 2014 Mar 6;9(3):e90613. doi: 10.1371/journal.pone.0090613

Figure 1. Delayed skin wound healing in Fpr double deficient Fpr1/2-/-mice.

Figure 1

A, representative pictures of skin wound of WT and Fpr1/2-/- mice. A 6-mm full-thickness (including the Panniluluscarnosus) skin was excised from the right and left upper paravertebral regions of each animal and the injured areas were measured daily using NIH Image J software (version 1.37) (n = 5). B, the areas of wounds. Mice were punched to generate two 6-mm full thickness skin wounds with or without IP injection CRAMP (10 µg/100 µl) or Boc-2 (5 µM, 100 µl) (n = 15). The areas of wound were calculated. *, significantly increased wound area in Fpr1/2-/-and Boc-2 treated mice, compared with the wound area of WT mice at the same time points (p< 0.05).