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. 2014 Mar 6;9(3):e90613. doi: 10.1371/journal.pone.0090613

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This is an open-access article distributed under the terms of the Creative Commons Public Domain declaration, which stipulates that, once placed in the public domain, this work may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose.

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A-C, chemokine production of skin wound at 72 h (n = 15). WT and Fpr-deficient mice were subjected to full-thickness skin wound and the wounds were harvested at 72 h after injury and then homogenized for chemokine measurement with ELISA. D, homogenate-induced migration of parental and Fpr-transfected HEK293 cells. Migrating cells in response to different concentration of the homogenate in 3 HPF were counted. *, significantly increased migrating cells in response to homogenates as compared to medium control (0) (p<0.05). E, chemotactic activity of skin homogenates for neutrophils from WT and Fpr-deficient mice. *, significantly increased migrating neutrophils in response to homogenates as compared to medium control (0) (p<0.05).