Table 2.
Statistically significant glycans and corresponding putative structures.
| [M] | ACN | Category Composition |
Putative Structure |
P | Duodenal Ulcer | Gastric Cancer | ||
|---|---|---|---|---|---|---|---|---|
| FDR Adj |
(%) | 95% CI | (%) | 95% CI | ||||
| 1234.426 | 10% | High Mannose 5Hex,2HexNAc |
|
0.093 | −43.6 | −69.6 , 4.5 |
−37.5 | −63.4, 6.6 |
| 1275.455 | 10% | Complex 4Hex,3HexNAc |
|
0.044 | −37.9 | −60.4, − 2.7 |
−33.3 | −54.8, −1.6 |
| 1396.488 | 10% | High Mannose 6Hex,2HexNAc |
|
0.008 | −47.3 | −67.4, − 14.9 |
−45.8 | −64.2, − 18.0 |
| 1421.520 | 10% | Complex 4Hex,3HexNAc,1Fuc |
|
0.025 | −30.2 | −49.7, − 3.1 |
−28.6 | −46.2, −5.2 |
| 1437.510 | 10% | Hybrid 5Hex,3HexNAc |
|
0.008 | −41.6 | −60.9, − 12.8 |
−43.0 | −59.8, − 19.4 |
| 1462.547 | 20% | Complex 3Hex,4HexNAc,1Fuc |
|
0.004 | 16.4 | −24.6, 79.9 |
80.8 | 24.7, 162.0 |
| 1519.587 | 20% | Complex 3Hex,5HexNAc |
|
0.054 | 25.8 | −10.6, 76.9 |
42.8 | 6.7, 91.1 |
| 1558.549 | 10% | High Mannose 7Hex,2HexNAc |
|
0.008 | −32.8 | −54.3, − 1.4 |
−39.3 | −56.5, − 15.3 |
| 1599.587 | 20% | Hybrid 6Hex,3HexNAc |
|
0.044 | −10.5 | −39.9, 33.2 |
35.2 | −3.7, 89.9 |
| 1624.596 | 10% | Complex 4Hex,4HexNAc,1Fuc |
|
0.076 | −18.3 | −40.2, 11.7 |
−24.6 | −42.5, −1.2 |
| 1640.602 | 10% | Complex 5Hex,4HexNAc |
|
0.018 | −14.0 | −38.1, 19.3 |
−31.3 | −48.3, −8.8 |
| 1665.622 | 10% | Complex 3Hex,5HexNAc,1Fuc |
|
0.008 | 29.8 | 2.5, 64.4 | 35.9 | 10.7, 66.7 |
| 1665.622 | 20% | Complex 3Hex,5HexNAc,1Fuc |
|
0.030 | 22.6 | −23.0, 95.3 |
69.9 | 14.2, 152.7 |
| 1720.595 | 10% | High Mannose 8Hex,2HexNAc |
|
0.044 | −21.8 | −44.7, 10.5 |
−29.4 | −47.7, −4.7 |
| 1770.662 | 10% | Complex 4Hex,4HexNAc,2Fuc |
|
0.032 | −5.5 | −28.9, 25.7 |
−23.9 | −40.5, −2.5 |
| 1770.662 | 20% | Complex 4Hex,4HexNAc,2Fuc |
|
0.030 | −33.3 | −53.7, − 3.9 |
−33.8 | −51.5, −9.6 |
| 1786.657 | 10% | Complex 5Hex,4HexNAc,1Fuc |
|
0.008 | −18.1 | −45.1, 22.1 |
−40.5 | −57.9, − 15.9 |
| 1786.657 | 20% | Complex 5Hex,4HexNAc,1Fuc |
|
0.056 | −26.8 | −47.3, 1.5 | −27.7 | −45.3, −4.4 |
| 1843.676 | 10% | Complex 5Hex,5HexNAc |
|
0.072 | −7.5 | −31.7, 25.2 |
−22.9 | −40.7, 0.2 |
| 1882.650 | 10% | High Mannose 9Hex,2HexNAc |
|
0.020 | −20.1 | −45.5, 17.1 |
−35.5 | −53.7, − 10.2 |
| 1948.723 | 10% | Hybrid 6Hex,4HexNAc,1Fuc |
|
0.025 | −26.6 | −46.5, 0.7 | −29.3 | −46.2, −7.0 |
| 2660.913 | 40% | Complex 7Hex,6HexNac,1NeuAc |
|
0.050 | −22.9 | −38.3, 3.7 | 1.3 | −16.4, 22.9 |
● Mannose (Man) ■ N-acetylglucosamine (GlcNAc) ○Hexose (Hex) □ N-acetylhexosamine (HexNAc) ▲ Fucose (Fuc) ◆ Sialic acid (NeuAc)