Table 2.
Subject demographic data (skin)
DLE+/SLE+ | DLE+/SLE− | Psoriasis | Normal | |
---|---|---|---|---|
N | 10 | 10 | 5 | 10 |
Age at visit, yr (SD) | 46 (13) | 41 (11) | 58 (6) | 44 (8) |
Gender (M/F) | 2/8 | 2/8 | 1/4 | 1/9 |
Ethnicity, No. (%) | ||||
Caucasian | 2 (20%) | 0 (0%) | 5 (100%) | 8 (80%) |
African American | 6 (60%) | 8 (80%) | 0 (0%) | 2 (20%) |
Hispanic | 2 (20%) | 2 (20%) | 0 (0%) | 0 (0%) |
Asian | 0 (0%) | 0 (0%) | 0 (0%) | 0 (0%) |
Other | 0 (0%) | 0 (0%) | 0 (0%) | 0 (0%) |
CLASI activity score, mean (SD) | 12 (12) | 8 (6) | N/A | N/A |
CLASI damage score, mean (SD) | 14 (14) | 12 (5) | N/A | N/A |
SLEDAI score, mean (SD) | 4 (3) | 0 (0) | N/A | N/A |
PASI score, mean (SD) | N/A | N/A | 7 (5) | N/A |
Disease Duration, yr (SD) | 10 (9) | 7 (8) | 5 (7) | N/A |
Lupus medications at study visit, No. (%) | ||||
Topical/Intralesional Corticosteroids | 5 (50%) | 7 (70%) | 2 (40%) | N/A |
Topical Immunomodulators | 1 (10%) | 0 (0%) | 0 (0%) | N/A |
Hydroxychloroquine | 4 (40%) | 5 (50%) | 0 (0%) | N/A |
Chloroquine | 1 (10%) | 0 (0%) | 0 (0%) | N/A |
Prednisone | 3 (30%) | 0 (0%) | 0 (0%) | N/A |
Mycophenolate mofetil | 1 (10%) | 1 (10%) | 0 (0%) | N/A |
Acitretin | 0 (0%) | 0 (0%) | 1 (20%) | N/A |
None | 0 (0%) | 0 (0%) | 3 (60%) | N/A |
SLE criteria, No. (%)a | ||||
Malar rash | 4 (40%) | 0 (0%) | N/A | N/A |
Discoid rash | 10 (100%) | 10 (100%) | N/A | N/A |
Photosensitivity | 9 (90%) | 7 (70%) | N/A | N/A |
Oral ulcers | 5 (50%) | 3 (30%) | N/A | N/A |
Arthritis | 6 (60%) | 0 (0%) | N/A | N/A |
Serositis | 2 (20%) | 0 (0%) | N/A | N/A |
Renal disorder | 3 (30%) | 0 (0%) | N/A | N/A |
Hematological disorder | 7 (70%) | 2 (20%) | N/A | N/A |
Anti-nuclear antibody | 10 (100%) | 3 (30%) | N/A | N/A |
Immunological disorder | 7 (70%) | 0 (0%) | N/A | N/A |
Mean # of SLE criteria (SD) | 6 (1) | 3 (1) | N/A | N/A |
None of the DLE patients had neurological disorder.
Abbreviations: CLASI = Cutaneous Lupus Disease Activity and Severity Index; DLE = discoid lupus erythematosus; PASI = Psoriasis Activity and Severity Index; SLE = Systemic Lupus Erythematosus; SLEDAI = Systemic Lupus Erythematosus Disease and Activity Index