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. Author manuscript; available in PMC: 2015 Feb 1.
Published in final edited form as: Eur J Immunol. 2013 Nov 15;44(2):450–459. doi: 10.1002/eji.201343477

Figure 3. Th2 responses in stat4−/− mice during L. donovani infection.

Figure 3

Th2 cytokine production by splenocytes from L. donovani infected WT and stat4−/− BALB/c mice or WT and stat4−/− C57BL/6 mice stimulated with 20μg/ml LdAg. IL-10 (A and C) and IL-4 (B and D) were measured by ELISA. Data shown are the mean ± SE of triplicates from four or five individual mice per group and are representative of three individual experiments. ** P < 0.01, * P < 0.05 using unpaired t test.

Th2 cytokine mRNA expression by spleen tissue from L. donovani infected WT and stat4−/− BALB/c mice or WT and stat4−/− C57BL6 mice. IL-10 mRNA (E and G) and IL-4 mRNA (F and H) were measured by Real Time PCR. *, P < 0.05 and **, P < 0.01 using unpaired t test.