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. Author manuscript; available in PMC: 2015 Feb 1.
Published in final edited form as: Cancer Prev Res (Phila). 2013 Nov 11;7(2):186–198. doi: 10.1158/1940-6207.CAPR-13-0276

Figure 5. Erb-041 treatment blocks EMT, PI3K/AKT and WNT/β-catenin pathways in UVB-induced tumor lesions.

Figure 5

Immunofluorescence staining showing expression of (A) E-cadherin, (B) N-cadherin, Snail, Slug and Twist; (C) western blot analysis showing the expression of E-cadherin, N-cadherin, Twist, Snail, Slug, MMP-2 and -9; (D) graphs representing the effects of Erb-041 treatment to A431 and SCC13 cells on wound closure in scratch assay; (E) western blot analysis of p-PI3K(85KDa), PI3K(110KDa), p-AKT1/2/3(Ser473); (F) immunofluorescence staining showing co-expression of WNT7b and β-catenin; (G) western blot analysis of WNT3b, WNT7b and FZD1.