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. Author manuscript; available in PMC: 2015 May 1.
Published in final edited form as: Neurobiol Aging. 2013 Oct 22;35(5):1153–1161. doi: 10.1016/j.neurobiolaging.2013.10.088

Figure 1.

Figure 1

Percentages of fat, protein and carbohydrate in the control diet and the HCD; mice on the high calorie diet received 47% of their caloric intake from fat compared to just 18% for the mice on a normal diet (A). Both SNCA and WT littermates maintained on the control diet did not gain a significant amount of weight; only 7–13% of their original body weight (B). WT mice started on a HCD at 12 weeks of age experienced a 66% rise in body weight compared to baseline whereas SNCA mice maintained on a HCD gained only 17% of their original body weight on average (B). Data obtained from the Comprehensive Lab Animal Monitoring System (CLAMS) obtained after 12 weeks on either a normal or HCD showed no significant differences in food intake between the two strains for either the control diet (C) or HCD (D) for two rounds of the light-dark cycle (48 hours) as demonstrated by shading. Figure 1B was modified from the data used for Supplementary Figure 2 in Griffioen et al., 2012.

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