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. Author manuscript; available in PMC: 2015 May 1.
Published in final edited form as: Neurobiol Aging. 2013 Oct 22;35(5):1153–1161. doi: 10.1016/j.neurobiolaging.2013.10.088

Figure 3.

Figure 3

SNCA mice were hypoleptinemic and displayed increased hunger. Blood plasma leptin levels were significantly lower in SNCA mice compared to WT littermates at 36 weeks of age, after 24 weeks on the diets (p=0.03) (A). WT plasma leptin levels are also significantly elevated compared to SNCA after HCD (p=0.003) (A). The hunger/satiety test revealed that on a control diet, 24 week old SNCA mice consumed significantly more food within the same period of time after an overnight fast than WT littermates (p<0.03) (B). No differences in food consumption were noted between the strains for mice on the HCD (measured when the mice were 24 weeks old, and had been on the diets for 12 weeks).

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