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. 2014 Mar 6;9(3):e90825. doi: 10.1371/journal.pone.0090825

Figure 3. The reduced weight of BAT in the DKO mice subjected to a 20 h fast was not altered after cold exposure.

Figure 3

The mice were exposed to a cold environment (4°C) with or without prior fasting. (A and B) Original body weight (BW) of mice in each group before cold exposure. (A) BW of the mice included in Figures 4C and 4E before the experiment. (B) Left panel: BW of mice included in Figures 4D and 4F before fasting. Right panel: BW of mice included in Figures 4D and 4F after a 20 h fast but before cold exposure. (C and D) Weight of interscapular BAT in each group before and after cold exposure in the fed (C) and the fasted states (D). (E and F) The ratio of the BAT weight to the BW before fasting was calculated from the data shown above. Note that the BAT is significantly shrunk after fasting or cold exposure and that the reduced weight of BAT in the DKO mice after a 20 h fast was not altered after cold exposure. n = 4–5/group. *p<0.05; **p<0.01; ***p<0.001.