Figure 8. Genetic deletion of Chop protects against CLP induced mortality.
The survival rate of WT and CHOP KO mice (8 mice per group) was observed for 8 days after induction of sepsis by CLP (n=8–10 *, P=0.01). A group of CHOP KO mice was also treated with H2S 2h prior to CLP (CHOP KO vs CHOP KO+H2S P=0.9).