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. 2014 Mar 6;9(3):e90935. doi: 10.1371/journal.pone.0090935

Table 5. Antibiotic resistance in carriage and invasive 6B, 6A or 6C pneumococcal isolates over time.

Study year Serotype Carriage isolates, No (%) IPD isolates, No (%)
Total Non-susceptibility Total Non-susceptibility Resistance patterns*
Pen E Pen E T Pen-E E-T Pen-E-T
2002–2003 6B 71 47 (66.2) 59 (83.1) 199 108 (54.3) 171 (85.9) 85 (42.7) 60 45 39
6A 40 11 (27.5) 12 (30.0) 55 18 (32.7) 28 (50.9) 7 (12.7) 13 2 4
6C 12 7 (58.3) 7 (58.3) 16 4 (25.0) 6 (37.5) 1 (6.3) 3 1 0
2004–2005 6B 56 38 (66.7) 48 (85.7) 111 42 (37.8) 88 (79.3) 51 (46.0) 22 30 19
6A 58 14 (24.1) 16 (27.6) 56 19 (33.9) 29 (51.8) 13 (23.2) 10 4 8
6C 22 2 (9.1) 9 (40.9) 16 2 (12.5) 7 (43.8) 4 (25.0) 1 4 0
2006–2007 6B 21 10 (47.6) 12 (57.2) 72 27 (37.5) 60 (83.3) 35 (48.6) 15 22 12
6A 46 11 (23.9) 14 (30.4) 57 15 (26.3) 17 (29.8) 5 (8.8) 8 0 3
6C 25 11 (44.0) 12 (48.0) 22 10 (45.5) 16 (72.3) 10 (45.5) 4 5 5
2008–2009 6B 11 6 (54.6) 7 (63.6) 27 11 (40.7) 21 (77.8) 12 (44.4) 6 8 4
6A 28 6 (21.4) 6 (21.4) 37 11 (29.7) 14 (37.8) 4 (10.8) 7 2 1
6C 45 17 (37.8) 26 (57.8) 59 30 (50.9) 46 (78.0) 38 (64.4) 4 16 22
2010–2011 6B 11 6 (54.6) 5 (45.5) 12 7 (58.3) 10 (83.3) 8 (66.7) 2 3 4
6A 14 7 (50.0) 7 (50.0) 32 14 (43.8) 15 (46.9) 6 (18.8) 6 3 2
6C 88 29 (33.0) 67 (76.1) 91 21 (23.1) 71 (78.0) 60 (66.0) 5 44 16

Pen, penicillin; E, erythromycin; T, tetracycline.

*The main resistance phenotype is indicated in bold.