Table 1.
Genes showing >2fold change at P < 0.05 in 39,X Y* O whole brain based on the microarray analysis
|
Upregulated in 39,X
Y*
O brain | |||||
|---|---|---|---|---|---|
| Gene | Chromosome | Product | Fold change | P -value | Human orthologue |
|
Gm16432 |
1 |
Function unknown |
5.5 |
0.006 |
None |
|
Vmn2r86 |
10 |
Vomeronasal 2 receptor 86 |
3.6 |
0.03 |
None |
|
Sfi1 |
11 |
Sfi1 homolog, spindle assembly associated (yeast) |
3.3 |
0.007 |
SFI1 (22q12.2) |
|
Pisd-ps1 |
11 |
Phosphatidylserine decarboxylase, pseudogene 1 |
2.7 |
0.02 |
None |
|
Tagap1 |
17 |
T cell activation GTPase activating protein 1 |
2.4 |
0.01 |
None |
|
C1qc |
4 |
Complement component 1, q subcomponent, C chain |
2.3 |
0.002 |
C1QC (1p36.11) |
|
Fam177a |
12 |
Family with sequence similarity 177, member A |
2.2 |
0.004 |
FAM177A1 (14q13.2) |
|
Metap1d |
2 |
Methionyl aminopeptidase type 1D |
2.0 |
0.0003 |
METAP1D (2q31.1) |
|
Downregulated in 39,X
Y*
O brain | |||||
|
Gene |
Chromosome |
Product |
Fold change |
p-value |
Human orthologue |
|
Erdr1 |
Y |
Erythroid differentiation regulator 1 |
3.6 |
1.3x10−6 |
None |
|
Trdn |
10 |
Triadin |
3.1 |
0.03 |
TRDN (6q22.31) |
|
Gm12696 |
4 |
Pseudogenic RNA |
2.9 |
0.01 |
None |
|
Fut11 |
14 |
Fucosyltransferase 11 |
2.2 |
0.002 |
FUT11 (10q22.2) |
| AA388235 | 17 | Non-coding RNA | 2.1 | 0.03 | None |