Table 3. Association of PRR and molecules of the TLR signaling cascade with CSR to IgE.
OR* | 95% CI | P-value | p-value after mutliple testing | ||
TLR7 | 1.33 | 1.13 | 1.57 | 0.001 | 0.063 |
TLR9 | 1.37 | 1.16 | 1.61 | 0.001 | 0.032 |
TLR10 | 0.90 | 0.83 | 0.98 | 0.017 | 0.089 |
IRAK2 | 1.23 | 1.04 | 1.45 | 0.014 | 0.080 |
HLA-DRA | 1.30 | 1.08 | 1.55 | 0.005 | 0.045 |
SOCS6 | 1.14 | 1.03 | 1.27 | 0.012 | 0.095 |
TRIAD3 | 1.49 | 1.09 | 2.02 | 0.012 | 0.084 |
Boldface values are significant (p<0.05).
*adjusted for sex, age, mother atopic sensitization and father atopic sensitization.
OR, odds ratio of farmers’ children compared with non-farmers’ children.