Table 1.

SWI/SNF subunits with cardiovascular phenotypes based on mouse knockout studies

Subunit	Cardiomyocytes	Vascular Endothelial Cells	Pericytes	Neural Crest
BRG1	Hypoplastic right ventricle, thin myocardium Shortened outflow tract Lack of septum Hypotrabeculation Lack of cardiac jelly	Yolk sac defects Coronary vessel death in adults if also BRM deficient	Patent ductus arteriosus Ventricular -septal defects Dilated cardiac chambers	Shortened outflow tracts Vascular defects
BAF250A	Developmental delay of right ventricle Defective formation of outflow tract Defective formation of ventricular septum Hypotrabeculation Cardiac progenitor cell differentiation in vitro	N.D.	N.D.	N.D.
BAF180	Hypoplastic ventricles Defective formation of ventricular septum	Coronary vessel defects	N.D.	N.D.
BAF60C	Hypoplastic ventricles Shortened outflow tract Hypotrabeculation Abnormal looping	N.D.	N.D.	N.D.
BAF155		Yolk sac defects	N.D.	N.D.

N.D. Does not necessarily infer there is no function for that cell type but can instead reflect either a lack of the appropriate conditional tissue-specific conditional mutation or insufficient phenotypic analysis.