Table 2. Weights and lipid content of selected organs and tissues of lean and overweight Wistar rats.
| organ/tissue | units | female control | male control | female cafeteria | male cafeteria | P values | ||
| sex | diet | |||||||
| brain | weight | g | 1.74 ±0.1 | 1.89 ±0.06 | 1.84 ±0.04 | 1.85 ±0.03 | NS | NS |
| lipid | mg/g | 77 ±2 | 62 ±11 | 87 ±9 | 69 ±8 | NS | NS | |
| g | 0.13 ±0.01 | 0.11 ±0.02 | 0.16 ±0.02 | 0.13 ±0.01 | NS | NS | ||
| liver | weight | g | 8.25 ±0.22 | 13.2 ±0.54 | 9.11 ±0.44 | 13.7 ±0.49 | <0.0001 | NS |
| lipid | mg/g | 43 ±1 | 41 ±1 | 50 ±3 | 59 ±3 | NS | <0.0001 | |
| g | 0.35 ±0.01 | 0.54 ±0.03 | 0.46 ±0.03 | 0.82 ±0.07 | <0.0001 | <0.0001 | ||
| gastrocnemius muscle | weight | g | 1.10 ±0.06 | 2.10 ±0.05 | 1.24 ±0.07 | 2.02 ±0.06 | <0.0001 | NS |
| lipid | mg/g | 29 ±2 | 32 ±3 | 48 ±5 | 36 ±4 | NS | 0.0053 | |
| mg | 32 ±3 | 67 ±8 | 60 ±7 | 72 ±8 | 0.0026 | 0.0252 | ||
| calculated muscle mass | weight | g | 79.2 ±1.2 | 127 ±2.2 | 81.7 ±1.1 | 127 ±2.9 | <0.0001 | NS |
| lipid | g | 2.30 ±0.13 | 4.00 ±0.39 | 3.92 ±0.35 | 4.55 ±0.51 | 0.0052 | 0.0084 | |
| interscapular BAT | weight | g | 0.50 ±0.04 | 0.53 ±0.06 | 0.69 ±0.07 | 0.77 ±0.09 | NS | 0.0046 |
| lipid | mg/g | 305 ±40 | 447 ±27 | 502 ±29 | 523 ±17 | 0.0118 | 0.0002 | |
| g | 0.21 ±0.03 | 0.24 ±0.03 | 0.35 ±0.04 | 0.40 ±0.04 | NS | 0.0004 | ||
| perirenal BAT | weight | g | 0.52 ±0.08 | 0.71 ±0.12 | 0.59 ±0.08 | 0.87 ±0.07 | 0.0163 | NS |
| lipid | mg/g | 416 ±70 | 522 ±36 | 538 ±20 | 580 ±28 | NS | 0.0491 | |
| g | 0.23 ±0.07 | 0.37 ±0.06 | 0.32 ±0.05 | 0.49 ±0.03 | 0.0101 | NS | ||
| subcutaneous WAT | weight | g | 6.65 ±0.71 | 11.4 ±0.80 | 11.5 ±2.55 | 17.5 ±2.12 | 0.0057 | 0.0055 |
| lipid | mg/g | 577 ±50 | 576 ±58 | 677 ±65 | 652 ±34 | NS | NS | |
| g | 3.95 ±0.64 | 6.55 ±0.79 | 8.38 ±2.50 | 11.4 ±1.45 | NS | 0.0067 | ||
| retroperitoneal WAT | weight | g | 2.95 ±0.23 | 6.97 ±0.77 | 6.67 ±0.98 | 10.9 ±0.63 | <0.0001 | <0.0001 |
| lipid | mg/g | 831 ±18 | 851 ±22 | 844 ±26 | 877 ±10 | NS | NS | |
| g | 2.44 ±0.15 | 5.93 ±0.70 | 5.64 ±0.91 | 9.52 ±0.47 | <0.0001 | <0.0001 | ||
| mesenteric WAT | weight | g | 3.76 ±0.42 | 4.73 ±0.37 | 6.45 ±0.77 | 6.80 ±0.90 | NS | 0.0017 |
| lipid | mg/g | 738 ±37 | 777 ±17 | 771 ±35 | 794 ±34 | NS | NS | |
| g | 2.85 ±0.44 | 3.70 ±0.31 | 4.93 ±0.54 | 5.41 ±0.76 | NS | 0.0022 | ||
| perigonadal WAT | weight | g | 6.48 ±0.89 | 5.98 ±0.44 | 14.1 ±2.06 | 9.10 ±0.57 | 0.0299 | 0.0002 |
| lipid | mg/g | 828 ±8 | 839 ±7 | 838 ±9 | 846 ±5 | NS | NS | |
| g | 5.38 ±0.77 | 5.01 ±0.36 | 11.87 ±1.83 | 7.70 ±0.50 | 0.0410 | 0–0003 | ||
Values are the mean ± sem of six different animals. Statistical significance of the differences between groups (two-way ANOVA); NS = not statistically significant (P>0.05). Data for calculated muscle mass are an extrapolation to total body muscle, calculated from net lean body mass and the data for gastrocnemius muscle. These data were not used for further calculations.