Table 3.
Distribution of covariates by anxiety and depression diagnoses.
| Covariate %(n) | No anxiety or depression n=159,482 |
Anxiety only n=22,457 |
Depression only n=24,721 |
Anxiety and Depression n=29,419 |
Chi-square p-value |
|---|---|---|---|---|---|
| Age (mean (95%CI)) | 64.5 (64.5–64.6) | 59.0 (58.9–59.1) | 60.5 (60.4–60.7) | 58.1 (58.0–58.2) | <.0001* |
| Gender | |||||
| Male | 93.0 (148,359) | 97.4 (21,868) | 92.2 (22,790) | 93.5 (27,512) | <.0001 |
| Female | 7.0 (11,123) | 2.6 (589) | 7.8 (1,931) | 6.5 (1,907) | |
| Race | |||||
| White | 77.3 (123,194) | 77.1 (17,316) | 84.3 (20,844) | 83.0 (24,422) | <.0001 |
| Non-White | 17.9 (28,576) | 20.4 (4,581) | 13.5 (3,336) | 15.4 (4,535) | |
| Unknown | 4.8 (7,712) | 2.5 (560) | 2.2 (541) | 1.6 (462) | |
| Marital | |||||
| Married | 58.2(92,777) | 56.6 (12,700) | 45.6 (11,260) | 47.1 (13,861) | <.0001 |
| Unmarried | 36.4 (58,088) | 41.4 (9,290) | 53.2 (13,157) | 51.7 (15,220) | |
| Unknown | 5.4 (8,617) | 2.1 (467) | 1.2 (304) | 1.2 (338) | |
| Insurance | |||||
| Additional | 48.0 (76,485) | 41.3 (9,281) | 41.6 (10,284) | 39.3 (11,548) | <.0001 |
| VA only | 52.0 (82,981) | 58.7 (13,174) | 58.4 (14,437) | 60.8 (17,871) | |
| Substance abuse | 10.8 (17,252) | 31.5 (7,062) | 30.3 (7,482) | 44.3 (13,042) | <.0001 |
| Nicotine/ personal history of tobacco use | 26.1 (41,606) | 41.2 (9,244) | 39.0 (9,645) | 46.9 (13,009) | <.0001 |
| Hypertension | 71.6 (114,228) | 76.0 (17,074) | 71.3 (17,627) | 74.6 (21,939) | <.0001 |
| Hyperlipidemia | 57.5 (91,759) | 67.0 (15,043) | 62.0 (15,328) | 67.5 (19,848) | <.0001 |
| Type 2 DM | 31.0 (49,380) | 33.3 (7,487) | 31.8 (7,866) | 33.0 (9,696) | <.0001 |
| Obesity | 44.9 (71,663) | 54.8 (12,295) | 54.2 (13,388) | 58.9 (17,312) | <.0001 |
| SSRI | 11.8 (18,879) | 61.3 (13,771) | 69.1 (17,071) | 78.9 (23,223) | <.0001 |
| TCA | 9.2 (14,671) | 21.6 (4,851) | 21.8 (5,386) | 28.4 (8,342) | <.0001 |
| SNRI | 2.1 (3,353) | 18.9 (4,249) | 21.9 (5,401) | 37.1 (10,899) | <.0001 |
| Other | 8.9 (14,153) | 45.2 (10,147) | 49.5 (12,229) | 66.4 (19,526) | <.0001 |
| Benzodiazepine | 14.0 (22,240) | 56.1 (12,590) | 41.9 (10,369) | 69.2 (20,344) | <.0001 |
All statistical tests are Chi-square tests unless indicated.
*
F-test (ANOVA)