Figure 2. Double immunofluorescence staining of p300/CREB binding protein (CBP) and brain derived neurotrophic factor (BDNF) in the ipsilateral spinal dorsal horn (laminae I–IV) of vehicle-treated CCI rats.
Immunoreactivity of BDNF is localized in the cytoplasm and cell membranes surrounding immunoreactive p300 or CBP nuclei. Arrows indicate the co-localization of BDNF and p300 or CBP. Scale bar = 45 µm.