Skip to main content
. 2014 Mar 6;10(3):e1003936. doi: 10.1371/journal.ppat.1003936

Figure 2. GAG induces interleukin 1 receptor antagonist.

Figure 2

(A) IL-1 bioactivity measured as IL-2 production by NOB-1 cells stimulated with 50 ng/ml IL-1β in the presence of culture supernatant of unstimulated PBMCs (medium) or culture supernatants of PBMCs that were exposed to 10 µg/ml GAG for 24 hours (GAG conditioned medium) (n = 6 donors). (B) IL-1Ra, IL-1β and IL-1α concentrations in culture supernatants of human PBMCs stimulated with for 24 hours with 10 µg/ml GAG. Data are represented as mean +/− SEM.