Table 3. Independent prognostic factors for overall survival in the 196 patients with unresectalbe HCC according to univariate and multivariate analysis.

Variable	Hazard Ratio for Death	95%CI	P
Serum sodium	0.902	0.836–0.931	.000
Alkaline phosphatase	1.002	1.001–1.004	.001
ECOG PS	1.689	1.252–2.277	.001
Tumor size (>5 cm)	1.364	1.107–1.975	.001
Portal vein invasion	2.913	1.900–4.467	.000
Lymph node metastasis	2.032	1.049–3.934	.035
Distant metastasis	2.311	1.305–4.090	.004

Abbreviations: HCC: hepatocellular carcinoma; ECOG PS: Eastern Cooperative Oncology Group performance status.