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Physicochemical characterizations of NP-pArg-siRNA, and NP-PEI-siRNA. Quantitative evaluation of the conjugation of siRNA onto (a) NP-pArg and (b) NP-PEI by a gel retardation assay. Ratios of NP to siRNA correspond to mass of NP (iron equivalent) to mass of siRNA. (c) Volume based hydrodynamic size distribution of NP-pArg-siRNA and NP-PEI-siRNA. (d) Zeta potentials of NP-pArg-siRNA and NP-PEI-siRNA.
