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. Author manuscript; available in PMC: 2014 Mar 8.
Published in final edited form as: Mol Pharm. 2013 Sep 10;10(11):4032–4037. doi: 10.1021/mp4003738

Table 1.

Onset and duration measures of gastric re-acidification using BHCl after rabeprazole-induced hypochlorhydria. Onset of effect is characterized by the time to pH < 3, while the duration of effect is characterized by the rebound times to pH > 3 and pH > 4.

Subject Time to pH < 3 (Post-BHCl, min) Rebound Time to pH > 3 (min) Rebound Time to pH > 4 (min)
P-001 2.13 29 42
P-002 12.6 83 83
P-003 4.05 46 53
P-004 1.83 90 90
P-005 8.83 121 127
P-006 8.23 66 66

Mean (±SD) 6.27 (±4.29) 73 (±33) 77 (±30)