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. Author manuscript; available in PMC: 2014 Oct 3.
Published in final edited form as: J Phys Chem B. 2013 Sep 18;117(39):11584–11595. doi: 10.1021/jp4064966

Figure 5. Melting temperatures of RNA-DNA duplexes.

Figure 5

CD thermal ramps from 25°C to 95°C were monitored at the peak wavelength, 265 nm. Tms calculated from first derivative peaks are shown with error bars corresponding to the standard deviation from 3 independent measurements. Holm-Sidak All Pairwise Multiple Comparison revealed statistically significant differences (p<0.001) among group 1, the complementary duplexes (green), group 2, the hypoxanthine-adenine and hypoxanthine-uracil duplexes (cyan), and group 3, hypoxanthine-guanine and mismatch duplexes (magenta).