Figure 3. Histograms of the –log₁₀(p) of the Stouffer statistic from 50 modules of meta-analysis of 11 MDD studies and each single study.

Module #35 with 88 genes (red arrow and double-cross) have largest –log₁₀ transformed p-value of Stouffer’s statistic 4.4. The other four blue arrows and double crosses indicated that these four modules in all single studies have more than 14 (15% of the 88 genes in module #35) overlapped with module #35. See detailed description in text.