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. 2014 Mar 7;9(3):e90981. doi: 10.1371/journal.pone.0090981

Table 2. Alpha-diversity metrics for IBD subtype, disease activity, 6-MP use (Median (range)).

Reads per sample Coverage (%) Observed OTUs Chao1 Shannon
CD 8,053.5 97,4 477.2 684.0 6.6
(6,503.0–10,033.0) (94.8–99.3) (72.1–652.8) (99.7–1087.6) (1.4–7.1)
UC 8,097.0 97.0 499.3 753.4 6.7
(6,194–11,030) (95.8–98.6) (272.7–675.7) (433.1–1047.3) (5.5–7.7)
Exacerbation 7,921.0 97.4 493.3 726.3 6.7
(6,194.0–11,030.0) (95.8–99.3) (72.1–664.5) (99.7–1087.6) (1.4–7.7)
Remission 8,169.0 97.0 493.9 747.7 6.6
(6,503.0–10,013.0) (94.8–99.1) (160.6–675.7) (308.9–1067.3) (2.8–7.4)
Thiopurine use 8,193.0 97.8 338.9 489.3 5.8
(6,465.0–10,013.0) (96.2–99.3) (72.1–517.4)a (99.7–868.4)a (1.4–7.0)b
No thiopurine use 7,929.0 96.6 569.4 875.9 6.7
(6,194.0–11,030.0) (94.8–98.0) (406.9–675.7) (605.9–1087.6) (5.8–7.7)
a

significantly lower in thiopurine users, p<0.001.

b

significantly lower in thiopurine users, p<0.01.