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. Author manuscript; available in PMC: 2014 Aug 1.
Published in final edited form as: Kidney Int. 2013 Aug 21;85(2):404–415. doi: 10.1038/ki.2013.278
Variable GFR ACR
Estimate (95% CI) P-Value Estimate (95% CI) P-Value
Plasma Aldosterone 0 (−0.02, 0.01) 0.45 0.07 (−0.06, 0.2) 0.30
Plasma Renin Activity −0.13 (−0.61, 0.34) 0.58 −2.23 (−7.19, 2.74) 0.38
Recipient Age (years) −0.01 (−0.22, 0.19) 0.89 −0.39 (−2.18, 1.41) 0.67
Female Recipient −2.8 (−7.41, 1.81) 0.23 2.25 (−37.64, 42.14) 0.91
Caucasian Recipient −6.78 (−13.55, −0.01) 0.05 −3.68 (−62.07, 54.71) 0.90
Recipient BMI −0.13 (−0.62, 0.36) 0.59 −2.35 (−6.6, 1.89) 0.27
SBP (mmHg) 0.03 (−0.11, 0.16) 0.69 2.07 (0.72, 3.42) <0.01
DBP (mmHg) −0.01 (−0.25, 0.23) 0.94 −0.99 (−3.39, 1.4) 0.41
Hypertensive 2.37 (−2.69, 7.42) 0.36 32.57 (−10.89, 76.04) 0.14
Acute Rejection −1.11 (−6.89, 4.67) 0.71 66.42 (16.03, 116.81) 0.01
<3 HLA Matches −3.29 (−8.01, 1.44) 0.17 −24.64 (−65.65, 16.37) 0.24
Live Donor 2.66 (−3.12, 8.44) 0.36 −29.16 (−79.16, 20.83) 0.25
Donor Age (years) −0.28 (−0.49, −0.07) 0.01 1.49 (−0.34, 3.32) 0.11
Female Donor −4.02 (−8.86, 0.81) 0.10 19.53 (−22.46, 61.53) 0.36
Caucasian Donor 4.32 (−1.21, 9.85) 0.12 9.57 (−38.63, 57.77) 0.70
Cause of Kidney Disease
 DM reference reference
 HTN −0.79 (−10.64, 9.06) 0.87 −38.75 (−123.41, 45.91) 0.37
 PCKD 0.53 (−6.88, 7.93) 0.37 −12.6 (−77.3, 52.1) 0.70
 Other 2.59 (−3.15, 8.33) 0.89 −57.85 (−108.47, −7.23) 0.03
Losartan −1.6 (−6.21, 3) 0.49 3.43 (−36.8, 43.67) 0.87
Thiazides 0.44 (−7.81, 8.7) 0.92 −14.99 (−85.67, 55.7) 0.68
Loop Diuretics −2.05 (−7.51, 3.42) 0.46 −28.15 (−75.47, 19.16) 0.24
Tacrolimus + Rapamycin −2.7 (−12.46, 7.06) 0.59 −6.12 (−90.92, 78.69) 0.89
Tacrolimus + MMF + Pred. −5.23 (−14.13, 3.66) 0.25 −37.23 (−114.55, 40.1) 0.34
Tacrolimus + MMF + Pred. −5.17 (−16.9, 6.56) 0.38 −24.16 (−126.86, 78.55) 0.64
CSA + MMF −9.35 (−18.71, 0) 0.05 −8.69 (−90.61, 73.22) 0.83
CSA + MMF + Pred. −7.66 (−17.53, 2.22) 0.13 −14.26 (−100.15, 71.63) 0.74

SBP: systolic blood pressure; DBP: diastolic blood pressure; CSA: Cyclosporine