Table 6.

Cox proportional hazards regression with time-dependent covariates

All-Cause ESRD			Creatinine Doubling, All-Cause ESRD or Death
Variable	HR (95% CI)	P-Value	Variable	HR (95% CI)	P-Value
Plasma Aldosterone	1.01 (1.00, 1.0)	0.02	Plasma Aldosterone	0.998 (0.99, 1.003)	0.43
Plasma Renin Activity	0.82 (0.56, 1.1)	0.29	Plasma Renin Activity	1.02 (0.90, 1.1)	0.74
Age at Visit (years)	0.95 (0.89, 0.99)	0.04	Losartan	0.48 (0.21, 1.0)	0.07
SBP	1.03 (0.998, 1.0)	0.07	Tacrolimus + Rapamycin	2.37 (0.98, 5.7)	0.05
Loop diuretics	4.72 (1.01, 22.1)	0.05	Caucasian donor	0.18 (0.07, 0.4)	<0.01
Caucasian donor	0.26 (0.08, 0.8)	0.03	<3 HLA Matches	3.79 (1.56, 9.1)	<0.01
<3 HLA matches	6.35 (1.56, 25.8)	0.01	Hypertension	6.97 (2.23, 21.7)	<0.01
Hypertension	7.49 (0.85, 66.3)	0.07	Acute rejection (ever)	3.98 (1.80, 8.8)	<0.01

See separate file for Appendix.