Table 2. OLC1 expression in esophageal samples with different lesions.

	Expression of OLC1 protein			Total cases	Percent Positive (%)
Developmental stages	(−)(±)#	(+)#	(++)#
Normal adjacent tissues	21	4	0	25	16
Mi-DYS/Mo-DYS	18	7	3	28	35
S-DYs/CIS	11	15	7	33	66
Invasive Carcinoma	6	12	10	28	71

^#(−) = no staining; (±) = background or faint staining; (+) = positive staining; (++) = intense staining. Samples marked (+) or (++) were considered positive for OLC1 protein expression.

Significance was determined by Pearson chi-square test. S-DYs/CIS vs. Normal adjacent tissues, P<0.05; Invasive carcinoma vs. Normal adjacent tissues, P<0.05; Mi-DYS/Mo-DYS vs. Normal adjacent tissues, P>0.05; S-DYs/CIS vs. Mi-DYs/Mo-DYs, P<0.05; Invasive carcinoma vs. Mi-DYs/Mo-DYs, P<0.05; Invasive carcinoma vs. S-DYs/CIS, P>0.05.