a) Prevalence in the number of co-morbid conditions by recruitment cohort. Co-morbidities were defined as: smoking, diabetes, renal insufficiency, peripheral arterial disease, hypertension, and/or hypercholesterolemia. b)Prevalence in the number of severe coronary artery disease characteristics by recruitment cohort. Severe coronary artery disease was defined as: calcified stenoses, total occlusions, left main lesions ≥ 50%, type C lesions and/or triple vessel disease.