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. Author manuscript; available in PMC: 2015 Jan 1.
Published in final edited form as: Pediatr Res. 2013 Oct 14;75(0):8–13. doi: 10.1038/pr.2013.175

Figure 2.

Figure 2

Chlorhexidine inhibits L1 mediated neurite outgrowth. Cerebellar granule neurons are plated on either poly L-lysine (PLL) alone or PLL plus L1-Fc (L1), then ethanol (E, final concentration 25 mM), chlorhexidine vehicle (V, final concentration 1%)) or chlorhexidine in vehicle (CHG, final concentration 1.0 μg/ml CHG, 1% vehicle) are added to the media. The cells are grown for 24 h, fixed and neurite length measured. The mean of the neurite lengths for each condition is calculated, then the mean +/− SD is determined for 4 separate experiments and shown here. *p<0.001, PLL vs L1; **p<0.01, L1 vs L1+E; †p<0.05, L1+V vs L1+V+CHG. L1 vs L1+V is not significant (p=0.29).

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