Table 1.
Demographics and clinical characteristics of participants enrolled in the Clinical Outcome cohort between November 2006 and June 2010
| Younger subjects (n=74) Age<= 50 years |
Older subjects (n=32) Age >50 years |
p value | |
|---|---|---|---|
|
| |||
| Age, mean (SD) years | 43.7 (4.3) | 54.2(2.8) | <0.0001 |
|
| |||
| Male, n (%) | 50 (67.6) | 23 (71.9) | 0.660 |
|
| |||
| African American, n (%) | 68 (91.9) | 29 (90.6) | 0.830 |
|
| |||
| Education, mean (SD) years | 12.7 (2.2) | 13.0 (2.2) | 0.569 |
|
| |||
| Duration HIV diagnosis, mean (SD) years | 12.3 (5.8) | 15.1 (4.6) | 0.052 |
|
| |||
| CD4 nadir, cells/mm3 | 114.9 (96.9) | 79.3 (105.1) | 0.112 |
|
| |||
| CD4 current, cells/mm3 | 385.5 (201.2) | 350.2 (208.7) | 0.414 |
|
| |||
| HIV RNA, lg copies/μL | 1.47 (1.86) | 0.63 (1.49) | 0.029 |
|
| |||
| CSF HIV RNA, log copies/μL | 1.02 (1.56) | 0.58 (1.14) | 0.259 |
|
| |||
| Beck Depression Inventory | 10.5 (9.4) | 8.60 (10.0) | 0.376 |
|
| |||
| Substance abuse, n (%) | 62 (83.8) | 24 (77.4) | 0.440 |
|
| |||
| Co-morbidities: n (%) | 0.826 | ||
| 1. Incidental | 24 (32.4) | 10 (31.3) | |
| 2. Contributing | 49 (66.2) | 21 (65.6) | |
| 3. Confounding | 1 (1.4) | 1 (3.1) | |