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. 2013 Dec 18;59(2):661–670. doi: 10.1002/hep.26709

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Copyright © 2013 The Authors. Hepatology published by Wiley on behalf of the American Association for the Study of Liver Diseases.

This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Examples of the five most common injury patterns. (A) Acute hepatitic injury resulting from ciprofloxacin. (B) Chronic hepatitic injury resulting from isoniazid. (C) Acute cholestatic injury resulting from an anabolic steroid. (D) Chronic cholestatic injury resulting from amoxicillin-clavulanate (inset shows positive copper stain). (E and F) Cholestatic hepatitic injury resulting from duloxetine. For orientation, P indicates portal area, V indicates central vein, and arrows indicate canalicular cholestasis.