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. 2013 Dec 18;59(2):661–670. doi: 10.1002/hep.26709

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Copyright © 2013 The Authors. Hepatology published by Wiley on behalf of the American Association for the Study of Liver Diseases.

This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Histological features associated with outcome. (A) Zone 3 coagulative necrosis in a patient with severe injury resulting from duloxetine. (B) Microvesicular steatosis in a patient with fatal injury probably resulting from erythromycin. (C) Ductular reaction, cholangiolar cholestasis, and neutrophilic infiltration in a patient with severe injury resulting from duloxetine. (D) Granulomatous and eosinophilic inflammation in a patient with moderate (but hospitalized) injury probably resulting from atenolol.