Table 1.
Characteristics of 249 Patients With Suspected DILI Undergoing Biopsy
| N (%) | |
|---|---|
| Female | 144 (57.8) |
| Age, mean (range) | 48 (7-87) |
| Agents implicated | |
| Single agent | 172 (69.1) |
| Two agents | 56 (22.5) |
| ≥Three agents | 21 (8.4) |
| Most common agents implicated | |
| Amoxicillin/clavulanate | 19 (7.6) |
| Nitrofurantoin | 11 (4.4) |
| Sulfamethoxazole/trimethoprim | 9 (3.6) |
| Minocycline | 8 (3.2) |
| Ciprofloxacin | 7 (2.8) |
| Anabolic agents | 6 (2.4) |
| Azithromycin | 5 (2) |
| Levofloxacin | 5 (2) |
| Causality process completed | 208 (83.5) |
| Definite | 53 (21.3) |
| Very likely | 84 (33.7) |
| Probable | 33 (13.3) |
| Possible | 24 (9.6) |
| Unlikely | 14 (5.6) |
| DILIN severity score | |
| Mild | 40 (16.1) |
| Moderate | 39 (15.7) |
| Moderate-hospitalized | 83 (33.3) |
| Severe | 31 (12.5) |
| Fatal/transplanted | 15 (6.0) |