Table 4. Comparison of the mean [standard deviation (SD)] scores of different motor, psychiatric, fatigue and quality of life (PDQ-39) scales between subgroups of Parkinson’s disease (PD) patients regarding nutritional status (MNA).
| Scale | Domain | Abnormal nutritional status (n = 40) | Normal nutritional status (n = 106) | t-value | P-value |
| Baseline | Age (yr) | 61.3 (12.3) | 61.3 (9.8) | −0.02 | .982 |
| Disease duration (yr) | 8.2 (6.9) | 6.2 (4.6) | −2.02 | .045* | |
| Body mass index (BMI) (kg/m2) | 23.9 (3.8) | 26.6 (4.3) | 3.57 | .001* | |
| Daily levodopa dose | |||||
| Crude (mg) | 817 (450) | 841 (490) | 0.27 | .789 | |
| Weight-adjusted (mg/kg) | 13.55 (8.92) | 11.50 (6.94) | −1.46 | .146 | |
| PDQ39 | Mobility | 45.6 (26.6) | 19.4 (20.7) | −5.61 | <.001* |
| Activities of daily living (ADL) | 38.4 (28.9) | 18.0 (17.9) | −3.97 | <.001* | |
| Emotional well-being | 41.3 (22.4) | 22.1 (20.8) | −4.90 | <.001* | |
| Stigma | 22.0 (24.4) | 21.5 (25.4) | −0.11 | .913 | |
| Social support | 13.0 (17.2) | 5.1 (10.9) | −2.51 | .016* | |
| Cognitive impairment | 25.5 (20.5) | 13.5 (16.6) | −3.64 | <.001* | |
| Communication | 24.6 (23.9) | 10.3 (13.6) | −3.56 | .001* | |
| Bodily discomfort | 32.5 (20.3) | 16.4 (19.6) | −4.30 | <.001* | |
| Disease Severity | UPDRS: Part I-mental | 3.8 (3.2) | 1.3 (1.4) | −4.69 | <.001* |
| UPDRS: Part II-ADL | 15.9 (7.8) | 9.4 (5.8) | −5.17 | <.001* | |
| UPDRS: Part III-motor | 20.6 (10.1) | 13.3 (7.4) | −4.18 | <.001* | |
| UPDRS: Part IV-complications | 5.1 (3.4) | 2.9 (2.2) | −3.80 | <.001* | |
| a. Dyskinesia | 1.7 (2.5) | .8 (1.4) | −2.08 | .042* | |
| b. Wearing off | 2.3 (1.4) | 1.5 (1.2) | −3.06 | .003* | |
| UPDRS: Total | 45.9 (18.0) | 26.4 (13.6) | −6.50 | <.001* | |
| Hoehn & Yahr stage # | 2.5 (1.0) | 2.0 (1.5) | −4.55 | <.001* | |
| Schwab & England stage (%) | 71.2 (19.6) | 85.7 (13.9) | 4.29 | <.001* | |
| HADS | Anxiety | 8.8 (5.2) | 5.9 (4.9) | −3.08 | .002* |
| Depression | 9.0 (4.2) | 3.6 (3.5) | −7.77 | <.001* | |
| FSS | Fatigue | 5.4 (1.5) | 4.2 (2.0) | −4.00 | <.001* |
# Values are presented as median (IQR).