Table 1.
Characteristics of patients and controls. Data are expressed as number or mean (range).
Controls | ET | ET | |||
---|---|---|---|---|---|
JAK2V617F negative |
JAK2V617F positive |
||||
Number | 71 | 73 | 34 | 39 | |
Sex (M/F) | 33/38 | 27/46 | 16/18 | 13/26 | |
Age (years) | 47 (26-70) | 57 (23-81)* | 54 (23-77) | 60 (35-81)§ | |
Platelets (x10^9/L) | 249 (158-450) | 604 (223-1451)* | 666 (223-1451) | 556 (239-1427) | |
WBC (x10^9/L) | 6.4 (3.7-10.3) | 7.4 (3.2-13.3) | 7.2 (3.2-11.7) | 7.54 (5.1-13.3) | |
RBC (x10^6/L) | 4.8 (3.6-5.5) | 4.5 (3.0-6.6) | 4.4 (3.2-5.6) | 4.5 (3.0-6.6) | |
HCT (%) | 42 (35-48) | 41 (33-48) | 40 (33-46) | 41 (34-48) | |
THERAPY | NT | - | 11 | 4 | 7 |
ASA | - | 29 | 18 | 11 | |
HU | - | 5 | 3 | 2 | |
HU+ASA | - | 28 | 9 | 19 | |
THROMBOSIS (arterial/venous) | - | 26 (18/8) | 6 (6/3) | 20 (15/5)§ |
indicates p value < 0.05. ET essential thrombocythemia. WBC= White Blood Cell count; NT= not treated; ASA= Aspirin; HU= Hydroxyurea.