Table 1.
Compound # | Sample Code | Structure | Ras inhibition |
---|---|---|---|
1 | p-tBu-AGOH | No | |
2 | p-iPr-AGOH | No | |
3 | p-CF3O-AGOH | No | |
4 | AGOH | No | |
5 | p-PhO-AGOH | No | |
6 | m-CF3O-PGOH | No | |
7 | p-CF3S-PGOH | No | |
8 | m-CN-AGOH | Yes | |
9 | p-CF3O-PGOH | No | |
10 | BzDMAOH | No GGTI | |
11 | AFOH | No |