Table 3.
Predictive Biomarkers and Univariable Ordinal Logistic Regression Predicting Sinus Disease Severity
| Predictor | Controls* | Medical Cases* | Surgical Cases* | Crude OR (95%CI)† | P-value |
|---|---|---|---|---|---|
| IL-6 (log10 pg/mL) | 5.7 (1.7–17.7) | 2.6 (0.7–12.2) | 4.8 (3.1–13.6) | 0.72 (0.48–1.09) | 0.118 |
| IL-8 (log10 pg/mL) | 16.4 (11.7–35.0) | 12.6 (9.4–22.7) | 11.8 (9.0–21.8) | 0.41 (0.19–0.90) | 0.023 |
| TNF-α (log10 pg/mL) | 4.0 (2.6–5.5) | 4.3 (2.8–5.8) | 5.0 (2.3–8.7) | 1.93 (1.00–3.80) | 0.044 |
| GRO (log10 pg/mL) | 732 (487–973) | 641 (474–871) | 620 (506–952) | 0.41 (0.11–1.50) | 0.174 |
| BMI, kg/m2 | 27.9 (26–31) | 29.1 (26–31) | 29.8 (28–32) | 1.05 (1.03–1.14) | 0.163 |
| PMN count, ×103 | 3.8 (3.0–4.5) | 3.6 (2.8–4.2) | 3.3 (2.6–3.9) | 0.73 (0.57–0.94) | 0.011 |
Definition of abbreviations: OR = odds ratio; PMN = polymorphonuclear neutrophils; 95%CI = 95% confidence interval.
Values Expressed as Median (IQR).
Analysis was done between Medical Cases, Surgical Cases and Controls.