Table 5.
Predictive Biomarkers and Univariable Logistic Regression Predicting CRS with Polyps
| Predictor | CRS without polyps* N=52 |
CRS with polyps* N=11 |
Crude OR (95%CI)† | P-value |
|---|---|---|---|---|
| Eotaxin (log10 pg/mL) | 125 (93–172) | 79 (65–432) | 0.04 (0.00–1.49) | 0.082 |
| IFN-γ (log10 pg/mL) | 8.1 (4.8–20.1) | 7.6 (3.3–9.3) | 0.15 (0.02–1.32) | 0.087 |
| IL-4 (log10 pg/mL) | 3.2 (0.5–9.1) | 0.5 (0.1–2.2) | 0.52 (0.26–1.03) | 0.062 |
| IL-13 (log10 pg/mL) | 3.0 (0.5–18.7) | 1.4 (0.5–6.9) | 0.51 (0.21–1.27) | 0.148 |
| VEGF (log10 pg/mL) | 144 (88–247) | 64 (48–94) | 0.08 (0.01–0.70) | 0.022 |
| PMN count, ×103 | 3.6 (2.9–4.2) | 2.9 (2.5–3.4) | 0.41 (0.18–0.94) | 0.036 |
| Eosinophil count, ×10 | 16 (11–23) | 25 (18–43) | 1.04 (1–1.09) | 0.058 |
Definition of abbreviations: OR = odds ratio; IFN-γ = interferon-gamma; IL-4 = interleukin-4; IL-13 = interleukin-13;VEGF = vascular endothelial growth factor; PMN = polymorphonuclear neutrophils; 95%CI = 95% confidence interval.
Values Expressed as Median (IQR).