Table 2.
Responses to Therapy by used TKI.
N (%) | |||
---|---|---|---|
Overall (n=42) | Imatinib (n=27) | Dasatinib (n=15) | |
Complete Hematological Remission (CHR) | 38 (90) | 23 (85) | 15 (100) |
Complete Cytogenetic Remission (CCyR) | 24 (59) | 11 (41) | 13 (87) |
Complete Molecular Remission (CMR) | 8/32 (25) | 7/18 (39) | 1/14 (7)* |
Major Molecular Remission (MMR) | 16/32 (50) | 8/18 (44) | 8/14 (57) |
Minimal Residual Disease (MRD) negative by FC | 7/12 (58) | 2/5 (40) | 5/7 (71) |
among patients achieving MMR, SCT was performed before CMR achievement in 4/8 (50%) of patients on dasatinib and 1/8 (12%) of patients on imatinib.