Table 2. Statistical analysis of control subjects and subjects with alcohol dependence (Alcohol).

Summary of statistical analysis of KLF11 protein levels between human psychiatrically-normal control subjects and subjects with alcohol dependence (Alcohol)

	Control (n=12)	Alcohol (n=12)	Statistica	p-value
Age	49.25 ± 3.03	48.53 ± 2.37	0.083	0.934
Gender (% Male)	66.7 %	75.0 %	0.43	0.670
Race (%AAb)	33.3%	25.0 %	0.432	0.670
PMI	20.29 ± 2.2	23.36 ± 2.2	−0.975	0.339
Tissue pH	6.64 ± 0.09	6.49 ± 0.1	1.12	0.276
Storage Time	11.0 ± 0.76	10.83 ± 1.37	0.12	0.916
Smoker (%Yes)	66.7 %	50.0 %	−0.215	0.430
KLF11/actin	1.16 ± 0.25	2.09 ± 0.28	−2.45	0.0227

Categorical data compared with chi-square test with 1 degree of freedom

^aContinuous data compared with t-statistic with 22 degrees of freedom.

^bAA, African American.

1. General outcomes
   There were no significant differences between cohorts for demographic variables (Age, Gender, Race, PMI, pH, Storage Time and Smoking history).
2. The detailed analysis for KLF11
   In the univariate analysis using Student’s t-test and KLF11/actin ratio as the outcome, the mean value for subjects with alcohol dependence was significantly greater than control subjects (t=−2.45, df=10, p-value=0.0227).
   KLF11 was not significantly correlated with age, PHI, pH or storage time, nor was there a significant effect of gender, race or smoking status on KLF11 levels.
   There was no significant correlation between KLF11 and the age of onset or duration of alcohol dependence.