Table 3. Data Summary by LV Geometry and LV mass index groupings.
| Variable> | Categorical Variables: Frequencies (Percents) Continuous Variables: Mean (SD) or Geometric Mean [Q1,Q3] |
||||
|---|---|---|---|---|---|
|
| |||||
| Normal (N = 161) |
Concentric Remodeling (N = 32) |
Eccentric LVH (N = 58) |
Concentric LVH (N = 29) |
p-value† |
|
|
| |||||
| Age (yrs) | 16.01 (1.69) | 16.40 (1.79) | 16.40 (1.70) | 16.71 (1.34) | 0.13 |
| Gender Female | 78 (48.4%) | 18 (56.3%) | 24 (41.4%) | 12 (41.4%) | 0.58 |
| BP ≥120/80 | 31 (19.3%) | 8 (25.0%) | 26 (44.8%) | 15 (51.7%) | <.01 |
| Heart rate | 71.3 [64, 80] | 73.3 [66, 78] | 68.6 [62, 78] | 69.0 [62, 72] | 0.02 |
| Height (m) | 1.68 (0.09) | 1.67 (0.09) | 1.69 (0.09) | 1.72 (0.10) | 0.25 |
| BMI (kg/m2) ‡ | 26.49 [21.97, 31.86] |
25.99 [20.69, 32.01] | 34.26 [28.26, 42.59] | 30.71 [23.79, 37.51] | <.01 |
| BMI z-score | 1.19 (1.03) | 1.01 (1.16) | 2.04 (0.77) | 1.62 (0.94) | <.01 |
| Waist Circumference (cm) ‡ |
82.00 [71.00, 91.75] |
82.77 [70.05, 95.24] | 99.94 [84.50,118.10] |
92.30 [75.50,110.50] | <.01 |
| SBP (mmHg) ‡ | 110.98 [105.0,118.00] |
113.09 [104.0,120.44] |
116.87 [108.3,126.00] |
118.77 [109.7,127.33] |
0.01 |
| SBP z-score | −0.22 (0.84) | 0.02 (1.06) | 0.26 (1.04) | 0.32 (1.11) | 0.01 |
| DBP (mmHg) ‡ | 61.78 [57.67, 67.00] |
62.86 [58.67, 67.00] | 62.80 [57.67, 69.00] | 64.71 [60.00, 69.67] | 0.33 |
| DBP z-score | −0.35 (0.64) | −0.27 (0.60) | −0.33 (0.76) | −0.21 (0.61) | 0.71 |
| Heart rate (bpm) ‡ | 71.38 [64.0, 80.0] | 73.31 [66.0, 78.0] | 68.6 [62.0, 78.0] | 69.0 [62.0, 72.0] | 0.18 |
| HOMA (mg/dl) ‡ | 1.67 [0.99, 2.71] | 1.97 [1.29, 3.40] | 2.30 [1.38, 3.92] | 2.11 [1.23, 3.26] | 0.04 |
| Adiponectin (ug/ml) ‡ | 5.77 [4.00, 8.70] | 5.87 [3.65, 9.69] | 5.37 [3.80, 7.50] | 4.37 [2.65, 7.50] | 0.35 |
| IL6 (pg/ml) ‡ | 2.94 [2.00, 4.10] | 2.54 [2.00, 3.40] | 3.21 [2.20, 4.90] | 2.79 [1.95, 3.90] | 0.44 |
| PAI1 (ng/ml) | 56.60 (25.04) | 53.19 (29.45) | 69.81 (27.05) | 62.13 (30.75) | 0.03 |
| TNF-α (pg/ml) ‡ | 8.48 [7.00, 9.90] | 8.28 [7.30, 10.10] | 8.51 [6.85, 9.90] | 7.57 [6.75, 8.90] | 0.46 |
| TNF-αR (pg/ml) ‡ | 0.92 [0.70, 1.10] | 0.91 [0.60, 1.10] | 0.97 [0.80, 1.20] | 0.86 [0.70, 1.05] | 0.48 |
| hsCRP (mg/dl) ‡ | 0.66 [0.20, 1.70] | 0.87 [0.30, 1.95] | 1.18 [0.60, 3.15] | 0.65 [0.24, 1.77] | 0.04 |
| LVMI (g/[height in m]^2.7) | 30.24 (5.24) | 31.04 (5.15) | 43.10 (3.63) | 45.61 (5.26) | |
| LV RWT (cm/m of height) ‡ |
0.32 [0.29, 0.36] | 0.46 [0.42, 0.48] | 0.34 [0.32, 0.38] | 0.47 [0.42, 0.49] | |
| DTI Ratio | 5.38 (1.35) | 6.39 (1.76) | 5.69 (1.50) | 6.43 (1.33) | 0.01 |
†
Fishers exact test (categorical) or ANOVA F-test (continuous): any groups different (4-way comparison test)
‡
Data natural log transformed: geometric means with [first quartile, third quartile] presented
LVMI: left ventricular mass index; LV RWT: left ventricular relative wall thickness.
High LVMI: ≥36.9 (females), 39.4 (males); High LVRWT: ≥ 0.41